GSE16727

Platform: Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version)

Organism: Homo sapiens

Pdf version of the dendrogram

Set title:

Human keratinocytes exposed to tungsten carbide and tungsten carbide cobalt nanoparticles and cobalt chloride

Citation:

Busch W, Kühnel D, Schirmer K, Scholz S. Tungsten carbide cobalt nanoparticles exert hypoxia-like effects on the gene expression level in human keratinocytes. BMC Genomics 2010 Jan 27;11:65.

Set summary:

Comparison of transcriptional profiles after exposure of HaCaT cells to WC or WC-Co nanoparticles and respective amount of free cobalt in form of CoCl2 after 3 hours and 3 days of exposure. Genes responding especially to nanoparticles or leached cobalt ions should be determined.


Sample_name Description Type Treatment Dose NP_size
GSM419105 H2O 3h 1 HaCaT H2O control - -
GSM419106 H2O 3h 2 HaCaT H2O control - -
GSM419107 H2O 3h 4 HaCaT H2O control - -
GSM419108 H2O 3h 5 HaCaT H2O control - -
GSM419109 H2O 3h 6 HaCaT H2O control - -
GSM419110 WC 3h 1 HaCaT WC 30 µg/ml NA
GSM419111 WC 3h 2 HaCaT WC 30 µg/ml NA
GSM419112 WC 3h 4 HaCaT WC 30 µg/ml NA
GSM419113 WC 3h 5 HaCaT WC 30 µg/ml NA
GSM419114 WC 3h 6 HaCaT WC 30 µg/ml NA
GSM419115 WC-Co 3h 1 HaCaT WC-Co 33 µg/ml NA
GSM419116 WC-Co 3h 2 HaCaT WC-Co 33 µg/ml NA
GSM419117 WC-Co 3h 4 HaCaT WC-Co 33 µg/ml NA
GSM419118 WC-Co 3h 5 HaCaT WC-Co 33 µg/ml NA
GSM419119 WC-Co 3h 6 HaCaT WC-Co 33 µg/ml NA
GSM419120 CoCl2 3h 1 HaCaT CoCl2 - -
GSM419121 CoCl2 3h 2 HaCaT CoCl2 - -
GSM419122 CoCl2 3h 4 HaCaT CoCl2 - -
GSM419123 CoCl2 3h 5 HaCaT CoCl2 - -
GSM419124 CoCl2 3h 6 HaCaT CoCl2 - -
GSM419125 H2O 3d 1 HaCaT H2O control - -
GSM419126 H2O 3d 3 HaCaT H2O control - -
GSM419127 H2O 3d 4 HaCaT H2O control - -
GSM419128 H2O 3d 5 HaCaT H2O control - -
GSM419129 H2O 3d 6 HaCaT H2O control - -
GSM419130 WC 3d 1 HaCaT WC 30 µg/ml NA
GSM419131 WC 3d 3 HaCaT WC 30 µg/ml NA
GSM419132 WC 3d 4 HaCaT WC 30 µg/ml NA
GSM419133 WC 3d 5 HaCaT WC 30 µg/ml NA
GSM419134 WC 3d 6 HaCaT WC 30 µg/ml NA
GSM419135 WC-Co 3d 1 HaCaT WC-Co 33 µg/ml NA
GSM419136 WC-Co 3d 3 HaCaT WC-Co 33 µg/ml NA
GSM419137 WC-Co 3d 4 HaCaT WC-Co 33 µg/ml NA
GSM419138 WC-Co 3d 5 HaCaT WC-Co 33 µg/ml NA
GSM419139 WC-Co 3d 6 HaCaT WC-Co 33 µg/ml NA
GSM419140 CoCl2 3d 1 HaCaT CoCl2 - -
GSM419141 CoCl2 3d 3 HaCaT CoCl2 - -
GSM419142 CoCl2 3d 4 HaCaT CoCl2 - -
GSM419143 CoCl2 3d 5 HaCaT CoCl2 - -
GSM419144 CoCl2 3d 6 HaCaT CoCl2 - -

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