GSE42067

Platform: Affymetrix GeneChip Human Genome U133 Plus 2.0

Organism: Homo sapiens

Pdf version of the dendrogram

Set title:

Three human cell types respond to multi-walled carbon nanotubes and titanium dioxide nanobelts with cell-specific transcriptomic and proteomic expression [SAE cells]

Citation:

Tilton SC, Karin NJ, Tolic A, Xie Y et al. Three human cell types respond to multi-walled carbon nanotubes and titanium dioxide nanobelts with cell-specific transcriptomic and proteomic expression patterns. Nanotoxicology 2014 Aug;8(5):533-48.

Set summary:

To identify key biological pathways that define toxicity or biocompatibility after nanoparticle exposure, three human cell types were exposed in vitro to two high aspect ratio nanoparticles for 1 hr or 24 hr and collected for global transcriptomics. Transcriptional responses were measured by global microarray analysis of cells in culture.


Sample_name Description Type Treatment Dose NP_size
GSM1031905 SAE_CON_0_1hr-1 small airway epithelial (SAE) control - -
GSM1031906 SAE_CON_0_1hr-2 small airway epithelial (SAE) control - -
GSM1031907 SAE_CON_0_1hr-3 small airway epithelial (SAE) control - -
GSM1031908 SAE_MWCNT_10_1hr-1 small airway epithelial (SAE) multi-walled carbon nanotubes (MWCNT) 10μg/ml length 5-10μm, diameter 20-30nm.
GSM1031909 SAE_MWCNT_10_1hr-2 small airway epithelial (SAE) multi-walled carbon nanotubes (MWCNT) 10μg/ml length 5-10μm, diameter 20-30nm.
GSM1031910 SAE_MWCNT_10_1hr-3 small airway epithelial (SAE) multi-walled carbon nanotubes (MWCNT) 10μg/ml length 5-10μm, diameter 20-30nm.
GSM1031911 SAE_MWCNT_100_1hr-1 small airway epithelial (SAE) multi-walled carbon nanotubes (MWCNT) 100μg/ml length 5-10μm, diameter 20-30nm.
GSM1031912 SAE_MWCNT_100_1hr-2 small airway epithelial (SAE) multi-walled carbon nanotubes (MWCNT) 100μg/ml length 5-10μm, diameter 20-30nm.
GSM1031913 SAE_MWCNT_100_1hr-3 small airway epithelial (SAE) multi-walled carbon nanotubes (MWCNT) 100μg/ml length 5-10μm, diameter 20-30nm.
GSM1031914 SAE_TiO2_10_1hr-1 small airway epithelial (SAE) titanium nanobelts (TiO2-NB) 10μg/ml 7μm, 0.2μm, 0.01μm
GSM1031915 SAE_TiO2_10_1hr-2 small airway epithelial (SAE) titanium nanobelts (TiO2-NB) 10μg/ml 7μm, 0.2μm, 0.01μm
GSM1031916 SAE_TiO2_10_1hr-3 small airway epithelial (SAE) titanium nanobelts (TiO2-NB) 10μg/ml 7μm, 0.2μm, 0.01μm
GSM1031917 SAE_TiO2_100_1hr-1 small airway epithelial (SAE) titanium nanobelts (TiO2-NB) 100μg/ml 7μm, 0.2μm, 0.01μm
GSM1031918 SAE_TiO2_100_1hr-2 small airway epithelial (SAE) titanium nanobelts (TiO2-NB) 100μg/ml 7μm, 0.2μm, 0.01μm
GSM1031919 SAE_TiO2_100_1hr-3 small airway epithelial (SAE) titanium nanobelts (TiO2-NB) 100μg/ml 7μm, 0.2μm, 0.01μm
GSM1031920 SAE_CON_0_24hr-1 small airway epithelial (SAE) control - -
GSM1031921 SAE_CON_0_24hr-2 small airway epithelial (SAE) control - -
GSM1031922 SAE_CON_0_24hr-3 small airway epithelial (SAE) control - -
GSM1031923 SAE_MWCNT_10_24hr-1 small airway epithelial (SAE) multi-walled carbon nanotubes (MWCNT) 10μg/ml length 5-10μm, diameter 20-30nm.
GSM1031924 SAE_MWCNT_10_24hr-2 small airway epithelial (SAE) multi-walled carbon nanotubes (MWCNT) 10μg/ml length 5-10μm, diameter 20-30nm.
GSM1031925 SAE_MWCNT_10_24hr-3 small airway epithelial (SAE) multi-walled carbon nanotubes (MWCNT) 10μg/ml length 5-10μm, diameter 20-30nm.
GSM1031926 SAE_MWCNT_100_24hr-1 small airway epithelial (SAE) multi-walled carbon nanotubes (MWCNT) 100μg/ml length 5-10μm, diameter 20-30nm.
GSM1031927 SAE_MWCNT_100_24hr-2 small airway epithelial (SAE) multi-walled carbon nanotubes (MWCNT) 100μg/ml length 5-10μm, diameter 20-30nm.
GSM1031928 SAE_MWCNT_100_24hr-3 small airway epithelial (SAE) multi-walled carbon nanotubes (MWCNT) 100μg/ml length 5-10μm, diameter 20-30nm.
GSM1031929 SAE_TiO2_10_24hr-1 small airway epithelial (SAE) titanium nanobelts (TiO2-NB) 10μg/ml 7μm, 0.2μm, 0.01μm
GSM1031930 SAE_TiO2_10_24hr-2 small airway epithelial (SAE) titanium nanobelts (TiO2-NB) 10μg/ml 7μm, 0.2μm, 0.01μm
GSM1031931 SAE_TiO2_10_24hr-3 small airway epithelial (SAE) titanium nanobelts (TiO2-NB) 10μg/ml 7μm, 0.2μm, 0.01μm
GSM1031932 SAE_TiO2_100_24hr-1 small airway epithelial (SAE) titanium nanobelts (TiO2-NB) 100μg/ml 7μm, 0.2μm, 0.01μm
GSM1031933 SAE_TiO2_100_24hr-2 small airway epithelial (SAE) titanium nanobelts (TiO2-NB) 100μg/ml 7μm, 0.2μm, 0.01μm
GSM1031934 SAE_TiO2_100_24hr-3 small airway epithelial (SAE) titanium nanobelts (TiO2-NB) 100μg/ml 7μm, 0.2μm, 0.01μm

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